Sheafer Sequence Clustering
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protein sequence Clustering protein sequences hierarchical clustering sequence clustering

Sheafer Description

Sequence Clustering Sheafer is an utility to evaluate hierarchical clustering of protein sequences.Sheafer is a C++ implementation of various methods of multiple sequence alignment (MSA) clustering and specificity residues prediction.It currently implements:1) clustering by Diversity-Ambiguity Optimization (DAO) (see DAO.pdf);2) clustering by Contrast Entropy Optimization (CEO). This program is built upon Boost C++ libraries, expat XML parser and EO Evolutionary Computation Framework.

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